New model predicts lymphovascular invasion in pancreatic cancer

A new preoperative model effectively predicts lymphovascular invasion (LVI) in patients with pancreatic ductal adenocarcinoma (PDAC). Utilizing data from 1,009 patients across three hospitals, researchers identified key high-risk predictors such as age under 65, cachexia, and specific imaging findings. Their nomogram outperformed expectations, demonstrating strong predictive capability in both development and validation cohorts. High-risk patients showed significantly worse survival outcomes but benefited from neoadjuvant chemotherapy, highlighting the model’s potential for guiding treatment decisions.