In a retrospective analysis involving 183 colorectal liver metastasis patients, 69% completed two-stage hepatectomy (tsh), achieving a median overall survival of 65.3 months compared to just 20.6 months for those who failed to complete it. The study identified key prognostic factors linking successful resections to lower rates of extrahepatic disease, tumor size over 5 cm, and better chemotherapy responses. TSH coupled with perioperative systemic therapies significantly enhances long-term outcomes.
Journal Article by Boerner T, Gagnière J (…) D’Angelica MI et 11 al. in Ann Surg
Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.