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New Amylase Metric Predicts Pancreatic Fistulas Better

The “real amylase value” (RAV) significantly outperforms traditional drain amylase concentration in predicting postoperative pancreatic fistula (POPF) risk. An analysis of 198 patients revealed RAV’s area under the ROC curve reached 0.85 on postoperative day 1 and 0.89 on day 3, compared to 0.79 for classic measurement. Enhanced prediction lets surgeons optimize clinical management, refine drain removal timing, and target intervention strategies for high-risk patients, potentially improving recovery outcomes.

Journal Article by Emral AC, Çetinkaya G, Dikmen K and Kerem M in ANZ J Surg

© 2025 The Author(s). ANZ Journal of Surgery published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Surgeons.

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