Appendix, Gallbladder and Surgical Emergencies · 21 August 2025

Early VTE Prophylaxis Cuts Risk of Complications in Major Trauma Patients

Initiating pharmacologic venous thromboembolism (VTE) prophylaxis within 24 hours of major trauma admission dramatically lowers VTE risk by 42%, according to a large cohort study. Among 6,569 patients, those receiving early treatment experienced significantly fewer VTE events (2.8% compared to 7.8%) and showed reduced mortality rates (0.6% vs. 1.8%). Crucially, early initiation did not increase the risk of bleeding complications, supporting a shift towards this practice as standard care.

Journal Article by Kerwin AJ, Byerly S (…) Knudson MM et 4 al. in Ann Surg

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Waiting 60 days after pulmonary embolism before emergency surgery is linked to fewer complications.

Among 3,785 patients who had emergency general surgery after acute pulmonary embolism, those operated on at least 60 days later had markedly fewer major adverse events (adjusted OR 0.45, 95% CI 0.37–0.55).

Appendix, Gallbladder and Surgical Emergencies3 Nov 2026

Emergency surgery: lung complications raise death risk

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