GNAS Droplet Digital PCR Boosts Pancreatic Cyst Diagnosis Accuracy by 62%

GNAS droplet digital PCR effectively enhances the diagnosis of mucinous pancreatic cystic neoplasms (MPCNs) in fine-needle aspiration samples. In a cohort of 140 patients, this method achieved a 62% detection rate for MPCNs and identified 33% of inconclusive lesions as MPCNs, all with 100% specificity. Compared to traditional diagnostic methods, GNAS ddPCR markedly reduced diagnostic costs by 24%, positioning it as a valuable, cost-effective tool for clinicians.