Pelvic Exenteration Reshapes Outlook for Advanced Rectal Cancer Patients

Pelvic exenteration (PE) substantially increases curative options for patients with locally advanced or recurrent rectal cancer. R0 resections are now achievable in over 60% of cases thanks to improved surgical techniques and interdisciplinary collaboration. Success hinges on strategic patient selection, imaging, and tailored reconstructions based on tumor extent. Although morbidity can be significant, mortality has dropped in specialized centers, highlighting PE’s potential to redefine survival and quality of life for select patients.