Dynamic prognostic models for colorectal cancer with liver metastases significantly enhance survival predictions by integrating longitudinal laboratory markers. In a cohort of 976 patients, the most effective model outperformed static approaches, achieving area under the curve (AUC) values of 0.850 for five-year progression-free survival and 0.849 for overall survival. A web-based tool has been developed to apply these models clinically, allowing for real-time adjustments based on evolving patient data.
Journal Article by Chen Q, Deng Y (…) Zhao H et 4 al. in JAMA Netw Open