Index Admission Cholecystectomy Cuts Mortality and Readmission Rates in Acute Cholangitis

Cholecystectomy during the initial hospital admission for acute cholangitis significantly reduces in-hospital mortality and lowers readmission rates at 30 and 90 days. Among over 29,000 patients studied, those receiving surgery on admission exhibited a 60% lower mortality risk and substantially improved readmission outcomes, regardless of severity. Findings urge a re-evaluation of surgical timing in management protocols, highlighting a critical need for updated guidelines.