Optimal strategies for necrotizing pancreatitis: Early drainage and delayed surgery show promise

Early drainage with lavage and delayed step-up surgery demonstrate significant survival benefits in necrotizing pancreatitis, decreasing mortality and complications. In contrast, delayed video-assisted surgery leads to higher mortality rates. No significant differences between early and delayed intervention approaches were found. Tailoring treatment based on individual risk profiles is crucial as current evidence remains inconclusive, highlighting the urgent need for more rigorous randomized controlled trials to better inform clinical practice.