Mucinous appendix cancer (MAC) recurrence varies significantly by histology and critical postoperative periods. In a study of 385 patients, relapse risk was highest shortly after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: 1.0, 2.6, and 3.8 per 10 person-years for low-grade, high-grade, and signet-ring cell cancers, respectively. Researchers recommend individualized follow-up schedules every 5.5 to 18 months for low-grade and every 2-24 months for high-grade cases to optimize monitoring and intervention.
Journal Article by Kovalik V, Sardi A (…) Gushchin V et 5 al. in Ann Surg Oncol
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