New thresholds for fine-needle aspiration thyroglobulin redefine metastatic thyroid cancer diagnostics

Fine-needle aspiration thyroglobulin (fna-tg) enhances detection of lymph node metastases in papillary thyroid carcinoma. An optimal cutoff value of 0.865 ng/ml yields 80% sensitivity and 94.4% specificity. When paired with cytological and thyroglobulin ratio assessments, diagnostic accuracy soars to 96.6%. The fna-tg levels correlate with serum thyroglobulin and thyroid status, streamlining the identification of metastatic lymph nodes and improving patient management strategies.