Surgeons need to know how outcomes differ between pancreatic neuroendocrine tumors (pnet) and ductal adenocarcinoma (pdac) after surgery.

• After pancreatoduodenectomy, ideal outcomes were lower for pnet (44.2%) vs. pdac (56.9%), with significantly higher severe complications (31.2% vs. 19.0%) and readmission rates (23.6% vs. 15.3%).
• In distal pancreatectomy, pnet had better ideal outcomes (60.1% vs. 57.1%), despite higher pancreatic fistula rates (19.2% vs. 13.4%).

Consider patient-specific predictors like obesity and male sex to tailor surgical approaches and improve outcomes.