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Intestine and Lower Gastrointestinal Tract ·

Colorectal Cancer Risk in Patients with Rectal Bleeding Revealed

Single and double fecal immunochemical tests (FIT) effectively identify colorectal cancer risk in patients with rectal bleeding, crucial for surgical decisions.

  • FIT positivity is significantly higher in patients with rectal bleeding (34.7%) than those without (18.6%).
  • Sensitivity for detecting colorectal cancer is 98.0% in patients with rectal bleeding compared to 82.5% in those without.

Patients with rectal bleeding and two negative FIT results have virtually no risk of colorectal cancer, improving screening strategies.

  • Double FITs boost sensitivity to 100% in rectal bleeding cases, matching the non-bleeding group’s performance.

Journal Article by Shah F, Gunn F (…) Gerrard AD et 3 al. in BJS Open

© The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd.

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