Intestine and Lower Gastrointestinal Tract · 7 November 2025

Oral Antibiotics Cut Surgical Site Infections in Colorectal Ops

Oral antibiotic bowel preparation before elective colorectal surgery significantly reduces surgical site infections, influencing patient care decisions.

SSI rates dropped sharply with oral antibiotics: 14% vs. 41.9% without (p<0.01).
Hospital stays shortened for those receiving oral antibiotics: 8.09 days vs. 11.28 days (p<0.01).

This safe approach enhances recovery and may shift standard practices in colorectal surgery.

No adverse effects reported, indicating good tolerability of the regimen.

Journal Article by Mallesh K, Theakarajan R (…) Nagarajan R et 3 al. in Ann Coloproctol

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