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Intestine and Lower Gastrointestinal Tract ·

Early Surgery Beats Medical Treatment for Crohn’s Disease

Early ileocolic resection shows clear advantages over medical therapy for localized Crohn’s disease.

  • Crohn’s-related surgery rate in early ileocolic resection patients: 2.43% vs. 20.58% in medical treatment group.
  • Long-term biologic use significantly lower in surgery cohort: 18.38% vs. 72.91%.

Consider early surgery for patients not responding to medical treatment to improve remission and quality of life.

  • Five studies with 1,770 patients were analyzed, supporting the efficacy of early surgical intervention.

Journal Article by Hyon SS, Elsawwah JK (…) Nemeth ZH et 4 al. in J Crohns Colitis

© The Author(s) 2025. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.

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