Colorectal cancer (CRC) incidence and mortality are sharply increasing in East Asia, necessitating targeted surgical interventions and screening.

• South Korea leads with a 5.29% annual increase in CRC incidence, followed by China at 4.11%.
• Projections indicate a continued rise in China by 2050, while South Korea’s incidence stabilizes and Japan’s growth slows.

Males, particularly in China and South Korea, show faster incidence increases compared to females, emphasizing the need for gender-specific screening strategies.

• Aging populations and socioeconomic factors are significant contributors to the rising CRC burden.