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Intestine and Lower Gastrointestinal Tract ·

Watch-and-wait safe for rectal tumors beyond exam reach

Watch-and-wait management is viable for rectal cancers not palpable on exam, keeping patient outcomes comparable.

  • 3-year local regrowth-free survival rates: 81.4% for palpable vs. 74.3% for nonpalpable tumors.
  • 3-year disease-free survival rates: 80.8% for palpable vs. 74.3% for nonpalpable tumors.

Surgeons can confidently consider watch-and-wait for these cases without compromising efficacy.

  • Initial clinical responses don’t significantly affect long-term outcomes, but delayed responses may indicate faster risks for recurrence and organ loss.

Journal Article by Boysen M, Lai SH (…) Vogel JD et 7 al. in Ann Surg Oncol

© 2025. Society of Surgical Oncology.

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