Laparoscopic appendectomy reduces complications for acute appendicitis in Sub-Saharan Africa, offering a safer option for surgeons.

• Laparoscopic appendectomy lowers the risk of surgical site infections by 60% (risk ratio 0.40).
• It also leads to shorter hospital stays compared to open surgery.

Surgeons should consider adopting laparoscopic techniques where feasible to improve patient outcomes.

• Cost-effectiveness is also promising, though resource constraints remain a challenge.