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Appendix, Gallbladder and Surgical Emergencies ·

Pre-Hospital Whole Blood Shows Promise for Blunt Trauma Resuscitation

Whole blood (WB) transfusion in pre-hospital settings may enhance survival for blunt trauma patients compared to packed red blood cells (PRBCs).

  • Patients needing transfusions saw lower in-hospital blood requirements with WB (2 units vs. 3 PRBCs, p < 0.001).
  • No significant differences in overall mortality at 24 hours (3.5% for WB vs. 6.25% for PRBCs, p = 0.34) or hospital discharge (7.1% vs. 13.7%, p = 0.11).
  • However, WB showed a clear benefit for blunt injuries, with survival rates of 94.1% versus 79.5% for PRBCs (p = 0.02).

Consider adopting pre-hospital WB strategies for better outcomes in blunt trauma cases.

Journal Article by Caputo S, Piehl M (…) Duchesne J et 21 al. in J Am Coll Surg

Copyright © 2026 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.

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