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Intestine and Lower Gastrointestinal Tract ·

Transanal Surgery Offers R0 Resection for Rectal GISTs

Transanal endoscopic microsurgery (TEM) provides promising outcomes for rectal gastrointestinal stromal tumors (GISTs) while preserving function.

  • High rates of R0 resection were achieved in 13 patients with rectal GIST, underscoring the technique’s efficacy.
  • Tumor size should not automatically disqualify candidates for en-bloc excision with negative margins.

Neoadjuvant imatinib may help select borderline cases, but more extensive studies are needed to solidify patient criteria and outcomes.

Journal Article by Arezzo A, Distefano G (…) Morino M et 3 al. in Surg Endosc

© 2026. The Author(s).

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