Outcomes After Pancreatectomy for PNETs Are Similar Across Types

Pancreatectomy outcomes for pancreatic neuroendocrine tumors (PNETs) are consistent, regardless of whether they arise from sporadic cases or genetic syndromes like MEN1 and VHL.

• In a study of 1,527 patients, 73 had MEN1, 26 had VHL, and 1,428 exhibited sporadic PNETs.
• Resection rates varied, with R2 resection at 9.6% for MEN1, compared to 2.6% for sporadic and 3.8% for VHL cases.

Despite key differences in demographics and tumor characteristics, postoperative complications and survival rates remained equivalent. This suggests similar patient management strategies may be applied across these groups.