Surgeons should recognize that managing obesity could notably decrease cancer rates among patients.

• Obesity contributes to about 10% of new cancer diagnoses in the U.S., with specific cancers like endometrial and hepatobiliary seeing rates as high as 50%.
• Patients losing over 10% of their body weight through bariatric surgery or medication showed modest reductions in cancer incidence, ranging from -0.02% to -0.5%.

This suggests that integrating weight loss strategies in surgical care may help mitigate cancer risks.

• Inflammation and hormonal changes related to obesity complicate cancer development, emphasizing the need for comprehensive weight management.