Laparoscopic hemi-hepatectomy with portal vein resection offers effective options for patients with perihilar cholangiocarcinoma and portal vein involvement.

• Successfully completed in 450 minutes with minimal blood loss (200 ml).
• Achieved negative resection margins for a patient with Bismuth-Corlette type IV cholangiocarcinoma.

Consider this approach for select patients to improve surgical outcomes while maintaining safety.