Omitting antibiotics in mild cholecystitis reduces unnecessary use.

Perioperative antibiotics did not significantly lower infectious complications: 9% with antibiotics vs. 12% without.
Surgical site infections were also similar: 5% vs. 8%.

Surgeons can consider forgoing antibiotics in healthy patients with mild-moderate acute cholecystitis.

No differences in length of hospital stay or mortality were observed.
Further research is needed for high-risk patient populations.

Review by Jensen PUD, Graabæk F, Tolstrup MB and Shabanzadeh DM in Am J Surg

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