New Prognostic Tool for Stage III Rectal Cancer Survival

This study identifies how combining perineural invasion and lymph node ratio can improve survival predictions in stage III rectal cancer.

Perineural invasion-positive patients have significantly lower 3-year (74.7% vs 86.7%) and 5-year survival (61.7% vs 76.0%) compared to negative patients.
The integrated nomogram shows high accuracy (AUC 0.764-0.839) for cancer-specific survival, enhancing patient stratification.

Use this nomogram for personalized treatment decisions in your surgical practice.

Strong prognostic impact of perineural invasion found particularly in lymph node ratio ≤0.5 subgroups.

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