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Intestine and Lower Gastrointestinal Tract ·

Direct-to-Surgery for Stage II/III Rectal Cancer Yields Strong Results

For selected patients with stage II or III rectal cancer, a direct-to-surgery approach led to favorable 2-year oncologic outcomes.

  • Local recurrence rate was just 1% among patients undergoing low anterior resection.
  • Disease-free survival was 85%, and overall survival reached 99%.

Surprisingly, only 8% of patients required post-operative radiation therapy.

  • Preoperative MRI overstaged 51% of patients who were ultimately confirmed as stage I.

Journal Article by Kennedy ED, Simunovic M (…) Baxter NN et 14 al. in Ann Surg Oncol

© 2026. Society of Surgical Oncology.

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