Patient-led, home-based follow-up significantly reduces hospital visits for colorectal cancer survivors without compromising quality of life.

• In the as-treated analysis, patient-led follow-up decreased hospital contacts by 38%.
• No significant differences were found in quality of life or psychological distress between patient-led and standard follow-up groups.

This approach can ease the burden on healthcare systems while maintaining patient support.

• Note that 117 patients assigned to patient-led follow-up ultimately received standard follow-up care.