Hem-o-lok clips provide a safer and faster option for appendiceal stump closure in laparoscopic appendectomy compared to endoloops.

• Intra-abdominal abscess formation was 1.87 times less likely with hem-o-lok clips (p=0.035).
• Operative time was significantly shorter by an average of 5.41 minutes (p=0.019).

Surgeons may consider hem-o-lok clips for improved outcomes and efficiency in appendectomies.

• No significant differences were found in surgical site infections or hospital stays between techniques.