Plasma concentrations of procalcitonin and C reactive protein within 24 hours of surgery, along with their perioperative changes, were valuable predictors of major complications in elderly patients after non-cardiac surgery. Procalcitonin at 24 hours, C reactive protein at 24 hours, and their changes were particularly effective in predicting major complications, with good discriminatory ability. Journal […]
Author: STITCHES Newsletter
Advancements in Chronic Pancreatitis Management
Chronic pancreatitis is a result of repeated pancreatic inflammation leading to loss of function, causing symptoms such as abdominal pain and diabetes. The review highlights the latest research on diagnostic methods and treatment options, including genetic factors and surgical interventions for patients not responsive to medications. Promising clinical trials are ongoing to develop new medical […]
International Guidelines and Registry for Surgical Patients with Borderline-resectable and Locally Advanced Pancreatic Cancer
International experts in pancreatic surgery and cancer management developed and validated guidelines for the perioperative care of patients with borderline resectable (BR) and locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). The guidelines include 34 recommendations covering patient selection, timing of surgery, vascular reconstruction, lymphadenectomy, and more. Despite a low level of evidence for most clinical […]
Near-Infrared Fluorescence Imaging + Indocyanine Green Reduces Hypoparathyroidism Rates in Thyroid Cancer Patients
The study evaluated the impact of near-infrared fluorescence imaging plus indocyanine green fluorescence on postoperative hypoparathyroidism rates after total thyroidectomy and central neck lymph node dissection. The near-infrared fluorescence imaging + indocyanine green group showed significantly lower rates of both transient and permanent hypoparathyroidism compared to the control group and the near-infrared fluorescence imaging alone […]
Identification of a Pathomics Signature for Chemotherapy Benefits in Stage III Colon Cancer
Researchers developed and validated a pathomics signature based on 4 features to estimate prognosis and chemotherapy benefits in stage III colon cancer. The signature was found to be significantly associated with disease-free survival (DFS) and overall survival (OS) in training and validation cohorts. Patients with a low pathomics signature were more likely to benefit from […]
Specimen Extraction Site Affects Postoperative Incisional Hernia Risk After Minimally Invasive Right Colectomy
Minimally invasive right colectomy patients with midline specimen extraction have a higher risk of developing postoperative incisional hernia (ih) compared to those with pfannenstiel extraction. The study of 341 patients found that midline extraction was associated with a 25% ih rate, while pfannenstiel extraction had a 0% rate. Midline extraction was also linked to longer […]
C-Reactive Protein Predicts Liver-Specific Infections After Resection
Researchers found that postoperative day 3 and day 5 C-reactive protein levels have high predictive value for detecting liver resection-surgical site infections, with optimal cut-off values identified. This information can assist in ruling out infections and making decisions regarding hospital discharge in patients undergoing liver resection. Journal Article by Pattou M, Fuks D (…) Tzedakis […]
Age and Grade III hemorrhoids are associated with a higher likelihood of choosing hemorrhoidectomy as the initial treatment
Patients with grade III hemorrhoids were more likely to choose hemorrhoidectomy as the initial treatment compared to grade II. Additionally, younger patients (18-30 and 31-50 age groups) were more likely to opt for hemorrhoidectomy as the initial treatment compared to older patients. However, there were no significant differences in the time to hemorrhoidectomy based on […]
Impact of Emergency Surgery on Patient Reported Outcomes
Patients undergoing emergency general surgery felt they had no choice and were often excluded from decision-making. Females reported this more commonly. Patients with minor complications expressed less trust and communication issues, while those with major complications showed more confidence in their team. Patients not admitted to the ICU highlighted good communication. The severity of complications […]
Impact of ICU Admission on Physical and Mental Health Outcomes in Trauma Survivors
Physical impairment and mental health symptoms are prevalent in trauma survivors who spent significant time in the ICU. ICU patients had higher rates of new ADL limitations, worse SF-12 mental and physical scores, with factors like age, gender, race, education level, polytrauma, ventilator use, psychiatric illnesses, and delirium during ICU stay contributing to poor outcomes. […]