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In a hip multicenter study, researchers spilled the tea on adrenal cancer secrets. Analyzing 807 patients, they unveiled that mixed cortisol/androgen-secreting adrenal tumors play hard on survival, with worse overall survival compared to solo cortisol or androgen secrets. Notably, after a clean R0 surgery, the…
The hunt for equitable healthcare takes center stage as researchers uncover disparities in access to high-volume parathyroid surgeons in the US. Analysis of 2019 Medicare data reveals a skewed distribution, with 445 identified surgeons mostly concentrated in metropolitan areas. Shockingly, disadvantaged neighborhoods face longer distances…
In a Massachusetts study on primary hyperparathyroidism, researchers found that patients in socially vulnerable groups faced delays in surgeon evaluation, contributing to heightened risks of long-term complications. Among 1,082 patients, those in the highest vulnerability quartile had a 33% lower surgeon evaluation rate and were…
In the battle against adrenocortical carcinoma (ACC), researchers find surgical approach and extent matter less than tumor biology and margins in non-metastatic cases. A cohort study (2010–2019, 1,175 subjects) reveals laparoscopic surgery, often considered minimally invasive, correlates with worse survival in advanced disease (stage III).…
Surgery emerges as a viable treatment for stage IE primary thyroid lymphoma (PTL), with a cohort study of 1,596 patients (SEER database) and an external cohort of 38 patients (Shanghai, China). The 7.8-year SEER analysis showed no significant survival difference between surgery, surgery + radiotherapy/chemotherapy,…
Investigating primary hyperparathyroidism referrals, a study analyzed 1,100 patients and found that sex concordance (matching patient and practitioner sexes) correlated with increased specialist evaluations. Patients with concordant primary care practitioners had 32% higher odds of endocrinologist evaluation, and those with concordant endocrinologists had a 48%…
In the realm of thyroid cancer, where iodine treatment falls short for some, researchers explored a new ally. The thyroid-stimulating hormone receptor (TSHR) took the spotlight, showing up in 62% of patients' thyroid tissues. With a specially crafted radiolabeled compound, researchers witnessed TSHR's potential for…
In treating differentiated thyroid cancer, various surgical methods were compared for integrity, safety, efficacy, and patient experience. The study, including 7042 patients, found that the endoscopic transoral approach (EOA) excelled in maintaining surgical integrity and minimizing pain. Robotic bilateral axillo-breast approach (RBABA) protected parathyroid glands…
A groundbreaking study tracked 1613 patients with low-risk papillary thyroid carcinoma (PTC) who underwent radiofrequency ablation (RFA) for an impressive 58.5 months. Results unveiled a remarkable 4.3% local tumor progression rate, with a 95.7% disease-free survival at 8 years. Subcapsular tumor location and multifocality were…
Researchers scrutinized 3421 medullary thyroid cancer (MTC) cases to see if the 2009 American Thyroid Association (ATA) guidelines had a real impact. Post-2009, 72% of non-advanced MTC cases aligned with surgery guidelines, up from 67%. Discordant cases often featured females, older patients, and non-academic facilities.…
