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Ann Surg Oncol15 Feb 2024

Improved Survival with Neoadjuvant Chemotherapy in i-IPMN vs. PDAC

The study compared the response to neoadjuvant chemotherapy and overall survival in patients with invasive intraductal papillary mucinous neoplasm (i-ipmn) and de novo pancreatic ductal adenocarcinoma (pdac). The results showed that i-ipmn histology was independently associated with a lower risk of recurrence and death. Pathological,…

BMC Surg13 Feb 2024

Minimally Invasive Pancreaticoduodenectomy Benefits Frail Patients with Pancreatic Cancer

Frail patients with pancreatic cancer who underwent minimally invasive pancreaticoduodenectomy had improved postoperative outcomes compared to open surgery, according to a study. The analysis of pancreaticoduodenectomy cases for pancreatic ductal adenocarcinoma revealed lower rates of complications, major morbidity, and nonhome discharge for those who underwent…

BMC Surg13 Feb 2024

The Value of a Laparoscopic Approach in Pancreaticoduodenectomy

A propensity score-matched analysis compared the outcomes of laparoscopic pancreaticoduodenectomy (LPD) and open pancreaticoduodenectomy (OPD). LPD showed longer operative times, reduced blood loss, higher rates of pancreatic fistula and delayed gastric emptying, while postpancreatectomy hemorrhage, major morbidity, mortality, hospital stay, and readmissions were not significantly…

HPB (Oxford)13 Feb 2024

Prevalence and clinical characteristics of annular pancreas

A meta-analysis examined the clinical features and prevalence of annular pancreas (AP), a rare gastrointestinal congenital malformation. Analysis of 12,729,118 patients found a pooled prevalence of AP at 0.0045%. The most common comorbidity in adults and children with AP was duodenal obstruction, with pooled prevalence…