Liquid Biopsy Predicts Outcomes in Resected Pancreatic Cancer
In resected pancreatic ductal adenocarcinoma (PDAC), preoperative circulating tumor DNA (ctDNA) positivity is a strong predictor of poor overall and recurrence-free survival.
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Neighborhood Disadvantage Linked to 90-Day Mortality after Hepatectomy
An increased area deprivation index (ADI) correlates with a higher risk of 90-day mortality after major hepatectomy, particularly due to posthepatectomy liver failure.
Rural Patients with Colorectal Liver Metastases Face Care Gaps
Rural residency correlates with lower treatment rates and worse outcomes for colorectal liver metastases (CRLM).
KRAS and TP53 ctDNA Predict Survival in Localized Pancreatic Cancer
Detecting circulating tumor DNA (ctDNA) in patients with localized pancreatic ductal adenocarcinoma (PDAC) can help predict outcomes and guide surgical decision-making.
R1 Margins in Colorectal Liver Metastasis Surgery: A New Perspective
Microscopically positive margins (R1) after colorectal liver metastasis resection indicate worse outcomes but require context for interpretation regarding recurrence and repeat surgeries.
Comparative Evaluation of Fibrosis in Chronic Pancreatitis
A study found that fibrosis scores significantly differ among pancreatic surgery patients with and without chronic pancreatitis (CP), suggesting that reliance on fibrosis for diagnosis may lead to overdiagnosis of CP.
Neoadjuvant Radiotherapy in Pancreatic Cancer Shows No Survival Benefit
Adding radiotherapy to neoadjuvant chemotherapy for resectable pancreatic ductal adenocarcinoma improved pathologic response rates but failed to enhance overall or event-free survival.
Dual Nomograms Improve Prognostic Prediction in Pancreatic Cancer
A new set of dual nomograms can effectively predict overall survival and recurrence risk following pancreatic resection for ductal adenocarcinoma, aiding surgical decision-making and postoperative management.
Chronic Liver Disease Enhances Cholangiocarcinoma Outcomes
Patients with chronic liver disease (CLD) present with cholangiocarcinoma (CCA) at earlier stages and experience improved survival rates compared to non-CLD patients.
Mastering Robotic SMA Dissection in Pancreatic Surgery
The left posterior approach to the superior mesenteric artery during robotic pancreaticoduodenectomy offers excellent outcomes, including a high rate of R0 resection and manageable complication rates.