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Indocyanine green (ICG) significantly boosts procedural adjustments and tumor identification in minimally invasive liver surgery, according to findings involving 72 patients. Intraoperative ICG visualization proved "helpful" for 88% of surgeons, with meaningful differences in tumor positivity (12.2% in the ICG group vs. none in the…
Improved outcomes for patients with initially unresectable hepatocellular carcinoma are linked to the depth of radiographic response after systemic therapy prior to hepatectomy. In a study of 81 patients, radiographic response emerged as an independent prognostic factor for both recurrence-free and overall survival. Notably, achieving…
Neoadjuvant therapy (NAT) with FOLFIRINOX significantly enhances resectability and overall survival (OS) in patients with locally advanced pancreatic cancer (LAPC). This umbrella review of nine systematic reviews highlights that FOLFIRINOX leads to higher R0 resection rates compared to gemcitabine/nab-paclitaxel, with improved OS. Furthermore, surgical resection…
A novel nomogram has been developed to accurately predict late extraluminal postpancreatectomy hemorrhage (lepph) in patients with postoperative pancreatic fistula following pancreaticoduodenectomy. Utilizing a combination of key independent risk factors such as dorsal fluid accumulation and positive cultures in drainage fluid, the model demonstrated high…
A novel preoperative risk score predicts 90-day mortality after major liver resection, identifying five key risk factors: age ≥ 65 years, type 2 diabetes, a diagnosis of primary liver cancer, ASA ≥3, and extended hemihepatectomy. In a cohort of 513 patients, the 90-day mortality rate…
A novel preoperative model for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC) has been developed based on key clinical characteristics and serum biomarkers. Analyzing 1,027 patient cases, independent risk factors identified include hepatitis B virus infection, tumor size, and several alpha-fetoprotein markers. The model…
A novel surface microdialysis probe demonstrated safety and feasibility for monitoring liver metabolism after resection in 17 patients. Complications were minimal and consistent with Clavien-Dindo classification. Key metabolites, including glucose, lactate, and pyruvate, were analyzed, revealing significantly higher lactate in liver samples compared to plasma,…
A novel deep-learning network, RRM-TransUNet, significantly improves pancreas segmentation accuracy in CT images. Achieving a dice similarity coefficient of 93.82% and an average symmetric surface distance error of 1.12 mm on multiple datasets, this model integrates clinical expertise with user interaction. By using advanced techniques…
In a cohort study involving 1,027 patients with colorectal liver oligometastases, survival outcomes between microwave ablation (MWA) and surgical resection (SR) were compared. After a median follow-up of 39.8 months, no significant differences were found in overall survival rates (MWA: 70.6 months vs. SR: 83.2…
A comparative analysis of 203 pancreatic cancer patients between 2010-2015 and 2016-2021 revealed significant improvements in outcomes due to multidisciplinary treatment. Patients in the latter group had higher preoperative chemotherapy rates (95%) and lower morbidity and pancreatic fistula rates. Overall survival notably improved, from 26.0…
