Clinicians face numerous challenges incorporating advances in hepatocellular carcinoma (HCC) treatment into practice. Revised EASL guidelines highlight personalized surveillance based on risk assessment, standardized imaging procedures, and minimally invasive surgery for complex cases. They emphasize the critical role of liver transplantation, therapeutic transitions, and the integration of immunotherapy at different disease stages. A multidisciplinary team […]

Clinical outcomes from a study of 113 pancreatic cancer patients indicate that preserving the portal/superior mesenteric vein during pancreaticoduodenectomy results in similar oncologic outcomes to resection, with better vessel-functional outcomes. While there was no significant difference in R0 resection rates, overall survival, or recurrence-free survival, the preservation group experienced significantly lower rates of vein stenosis […]

A predictive and prognostic signature, named chemoresist, effectively identifies pancreatic ductal adenocarcinoma patients likely to benefit from adjuvant chemotherapy. In a multicenter study involving 551 patients, the chemoresist classifier demonstrated significant survival differences between high- and low-score patients, outperforming traditional TNM staging. It achieved higher predictive accuracy for two-year overall survival (AUC 0.788 vs. 0.636, […]

A meta-analysis of 10 studies involving 3,505 patients found that the no-drainage approach following left pancreatectomy is associated with a significantly lower incidence of postoperative pancreatic fistula (grade B/C) and a reduced length of hospital stay compared to the traditional drainage method. Major morbidity rates showed no substantial difference. These results suggest that avoiding prophylactic […]

A comprehensive consensus on robotic hepatectomy has been established by European experts, detailing techniques for different hepatectomy types. This expert report emphasizes best practices, from patient selection to postoperative care, aiming to standardize training and enhance surgical outcomes in robotic liver surgery. Addressing the current lack of consistent training materials, the findings encourage the safe […]

A comparative study evaluated the effectiveness of continuous local wound infiltration (LWI), four-quadrant transversus abdominis plane (4QTAP) block, and needle electrical twitching intramuscular stimulation (NETOIMS) for pain management in pancreaticoduodenectomy. The 4QTAP and NETOIMS techniques significantly reduced postoperative pain scores, opioid, and ibuprofen consumption, while promoting better functional recovery indicators like gait speed and peak […]

A multicentric study demonstrated the safety and efficacy of liver venous deprivation (LVD) in enhancing future liver remnant (FLR) volume prior to major hepatectomy. Out of 192 patients, LVD achieved a 100% technical success rate, with only a 2.6% rate of severe complications. FLR volume increased by an average of 61.7% within 27 days. Although […]