The study investigated the long-term outcomes of conservative management for complicated colonic diverticulitis. The results showed that non-operative treatment is effective and safe for selected patients, with recurrence rates of 38.1% and high severity recurrence rates of 11.1%. Lower CT stages and grade III diverticulitis were associated with higher recurrence rates. Chronic NSAID use was […]
Category: Intestine and Lower Gastrointestinal Tract
Endoscopic Powered Resection Device Shows Safety and Effectiveness for Scarred Colorectal Lesions
The multicenter, prospective, international clinical study assessed the safety and effectiveness of an endoscopic powered resection (EPR) system for scarred adenomatous colorectal lesions. Among the 45 per-protocol patients with 48 lesions treated solely with the EPR device, technical success was achieved in 98% of patients. Adverse events were limited, including two delayed self-limited bleeds and […]
Strategies to Reduce Ileus After Colorectal Surgery: Key Findings on Effective Interventions
Researchers conducted an umbrella review of 26 systematic reviews to determine strategies for reducing postoperative ileus after colorectal surgery. The most effective interventions included early oral feeding, chewing gum, and alvimopan. Early oral feeding accelerated bowel function return, while gum chewing reduced postoperative ileus by 45% and shortened time to first flatus and defecation. Coffee […]
Primary tumor resection does not impact event-free survival in patients with metastatic small bowel neuroendocrine tumors
The study investigated the impact of primary tumor resection on the development of disease-specific complications in patients with metastatic well-differentiated small bowel neuroendocrine tumors (SBNETs). The retrospective analysis of 180 patients showed that rates of event-free survival did not differ based on primary tumor management. Patients who underwent medical management first had a 23% complication […]
Comparison of Single-Port and Multi-Port Robotic Total Mesorectal Excision for Rectal Cancer: Similar Efficacy and Safety
Single-port robotic total mesorectal excision is comparable to multi-port robotic total mesorectal excision in terms of short-term clinical outcomes for rectal cancer treatment. A retrospective study of 128 patients found that the single-port system resulted in shorter operative times, smaller incision length, and shorter hospital stays. C-reactive protein levels were also lower in the single-port […]
The Kono-S Anastomosis Shows Low Complication Rates and Promising Long-Term Results in Crohn’s Disease Patients
In a multicenter study, 262 consecutive patients with Crohn’s disease underwent Kono-S anastomosis. The study reported very low rates of anastomotic failure (1.5%), reoperation (0.7%), and postoperative surgical site infection (6.1%). After a median follow-up of 49.4 months, surgical recurrence was found in 7.6% of patients. Perianal disease, urgent/emergent surgery, and postoperative use of steroids […]
EPA for Metastasis Trial 2 (EMT2): Phase 3 Protocol for CRC Liver Metastasis Surgery
The EPA for Metastasis Trial 2 (EMT2) study protocol aims to address the need for safe and cost-effective adjunctive treatment for advanced colorectal cancer (CRC). The trial evaluates the effect of EPA on CRC outcomes in patients undergoing liver resection surgery for CRC liver metastasis. The primary endpoint is CRC progression-free survival, with key secondary […]
Healthcare professionals identify training priorities to manage distress in young people with inflammatory bowel disease and a stoma
Healthcare professionals highlighted the need for training to recognize and manage distress in young people with inflammatory bowel disease (IBD) and a stoma. The study identified 19 training priorities, including addressing stigma, practicalities of stoma management, initiating conversations about distress, considering cultural beliefs, and techniques for assessing patient distress. These findings will inform the development […]
Long-term Survival Outcomes of Liver Resection for Metastatic Anal Squamous Cell Carcinoma
The study evaluated the outcomes of liver resection in patients with metastatic anal squamous cell carcinoma (SCC) to the liver. Among the 21 patients undergoing liver resection and/or ablation, 95% had undergone the Nigro protocol for the primary tumor, with 57% experiencing a complete response. The median overall survival was 32.2 months, and the 5-year […]
Neoadjuvant calcium electroporation is a safe and effective treatment for potentially curable colorectal cancer.
Neoadjuvant calcium electroporation was found to be a safe and feasible treatment modality for potentially curable colorectal cancer. In a study of 21 patients, no procedure-related complications were reported, and surgery was able to be performed as planned in 19 patients. Limited side effects and no significant impact on quality of recovery or inflammatory markers […]