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Rectal cancer treatment negatively impacts health-related quality of life (HRQOL). A multivariable prediction model developed in this study found that patient-reported outcomes from EORTC QLQ-C30, particularly fatigue and pain, were significant predictors of global HRQOL at all time points. These factors explained 55-65% of the…
Researchers examined outcomes of patients with acute colonic pseudo-obstruction (ACPO) and adherence to treatment guidelines. A total of 45 patients were identified, with 13 admitted under general surgery. Despite all patients receiving admission bloods, ACPO management, often overseen by general surgeons, may impact conservative treatment…
Comparison between stapled and hand-sewn ileal pouch-anal anastomosis in familial adenomatous polyposis patients showed that hand-sewn anastomosis was associated with better overall survival. The stapled group had higher rates of adenoma in the remnant rectum or anal transitional zone, metachronous rectal cancer, and mortality. Cox…
Rectal cancer survivors with low anterior resection syndrome showed improvement beyond 3 years post-proctectomy, with a decrease in mean syndrome score from 29.5 to 18.6. 31.5% experienced a shift from major to no/minor severity, while 3.4% required a new stoma. Long-term improvement was negatively associated…
The study compared perioperative complications, quality of life, and functional outcomes in patients with ulcerative colitis undergoing either 3-stage or modified 2-stage IPAA. Results showed similar rates of anastomotic leak, surgical site infection, ileus, quality of life, and pouch function between the two approaches. However,…
Neoplasia in the ileal pouch of patients with inflammatory bowel diseases or familial adenomatous polyposis is rare but poses a significant risk. Annual endoscopic surveillance is crucial for detecting dysplasia in high-risk patients. While dysplastic polyps in familial adenomatous polyposis are easily identifiable and removable,…
Researchers developed prediction models using preoperative data to assess short-term mortality risk following colorectal cancer surgery. The models showed good discrimination and calibration, with an area under the receiver operating characteristic curve of 0.88, 0.878, and 0.861 for 30-day, 90-day, and 1-year mortality, respectively. Subgroup…
CRC incidence is significantly higher in patients with high-risk adenomas (HRAs) diagnosed at colonoscopy, with a 1.53-fold increase in risk. However, patients with only distal pedunculated polyps without high-grade dysplasia do not have an increased CRC risk. The presence of certain risk factors explains most…
Quality of life trajectories after pelvic exenteration diverge into distinct classes, with most patients experiencing optimal outcomes. Two classes were identified for physical scores and three for mental and functional scores, with higher overall survival probabilities in the optimal trajectory class. Age, repeat surgery, neoadjuvant…
After implementing a reduction in postoperative laboratory testing following colorectal surgery, the intervention group experienced a 33% decrease in tests per hospital stay, a 26% decrease per day, and a 49% increase in test-free days, with no impact on length of stay or readmissions. The…
