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Rectal cancer patients who refused surgery despite incomplete response to neoadjuvant therapy had shortened overall survival (OS). Some patients converted to a complete clinical response (CCR) on subsequent staging, leading to prolonged OS. Patients with near CCR at initial endoscopic staging may benefit from prolonged…
Patients engaging with patient engagement technologies (PETs) during colorectal surgery showed improved outcomes. In a retrospective study, 89.1% activated PETs, completing surveys and health-checks. Those engaging more frequently experienced shorter lengths of stay, lower readmission rates, and fewer post-operative complications. Notably, patients who completed more…
Compared to upfront surgery, neoadjuvant chemotherapy for locally advanced colon cancer is associated with lower recurrence and mortality hazards, higher 5-year survival rates, and increased disease-free survival rates. Additionally, it reduces the risk of incomplete resection without significantly impacting perioperative complications or mortality. These findings…
Researchers evaluated total neoadjuvant therapy with immunotherapy for high-risk rectal cancer with proficient mismatch repair status. The study showed a pathologic complete response rate of 33.3%, with 48% achieving clinical complete response. R0 resection was achieved in all patients. Adverse effects were manageable, with nausea…
Implementing enhanced recovery pathways in rectal cancer surgery decreased short-term morbidity and length of hospital stay. However, adherence to these protocols did not show an improvement in long-term overall survival, cancer-specific survival, or disease-free survival compared to non-enhanced care. Therefore, while enhanced recovery pathways reduce…
Researchers conducted a randomized trial comparing stapled hemorrhoidopexy alone to stapled hemorrhoidopexy plus ligation anopexy for grade III-IV hemorrhoids. Although short-term outcomes were similar, the combined approach showed significantly better long-term results. After 36 months, the stapled-only group had a 16% recurrence rate, requiring redo…
High preoperative Fibrinogen-to-Prealbumin Ratio (FPR) and Glasgow Prognostic Score (GPS) are independently associated with worse overall survival in colorectal cancer patients after laparoscopic surgery. Combining FPR and GPS provides more accurate prognostic assessment, outperforming single indicators. Patients with elevated FPR and GPS values have a…
European hepato-pancreato-biliary surgeons generally agree on the definition of upfront resectable colorectal liver metastases based on future liver remnant volume and tumor biology. However, there is significant variability in the use of thermal ablation as an adjunct to surgery and perioperative systemic therapy. The survey…
Comparing 641 benign and 276 malignant colorectal resection patients, initial unadjusted analysis showed higher pain scores and more opioids for benign cases. Yet, in an enhanced recovery pathway emphasizing non-opioid strategies, regression analysis nullified the differences. Notably, both groups exhibited comparable pain levels and opioid…
Colorectal surgery among older adults is increasing, with geriatric conditions posing risks for poor outcomes. A systematic review found 25 cohort studies but no randomized trials on geriatric assessment in this context. Few studies focused on the domain of what matters most to geriatric patients,…
