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Tumor deposits are a strong indicator of poor outcome in stage III colorectal cancers. A new staging system, considering tumor deposits, showed higher predictive values and better patient stratification for oncologic outcome compared to the current system. Tumor deposits were correlated with adverse prognostic indicators,…
Surgeon-led geriatric service and good quality surgery are key in achieving good outcomes in older colorectal cancer surgery patients. A 10-year review of 233 patients aged ≥75 years or frail showed low 30-day mortality (1.7%) and complications (12.0%), with a median length of stay of…
Researchers validated Japanese criteria for locally resected pt1 colorectal carcinoma (CRC), assessing long-term outcomes in 4719 patients. Patients without risk factors had a low lymph node metastasis (LNM) incidence (1.8%), contrasting with risk-positive cases in Group B/C (10.3%). Group A, with risk factors, showed higher…
A predictive nomogram was developed to identify patients at risk for a positive circumferential resection margin (CRM) in rectal cancer surgery. Factors associated with positive CRM included tumor grade, lack of neoadjuvant chemotherapy, specific tumor histology, surgical approach, and other tumor characteristics. These findings can…
Among patients diagnosed with appendiceal adenocarcinoma after acute perforated appendicitis, half may have peritoneal metastasis. Prophylactic cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in cases without identified metastasis during CRS may lead to an encouraging rate of disease-free survival at 5 years, with a…
Increased utilization of induction chemotherapy in total neoadjuvant therapy for locally advanced rectal cancer led to higher pathologic downstaging rates compared to consolidation chemotherapy. From 2006 to 2017, 46.7% of patients experienced downstaging, with induction chemotherapy resulting in a higher rate of pathologic downstaging (58%…
Perioperative fluid management in colorectal surgery is discussed within enhanced recovery after surgery (ERAS) pathways. The review highlights the lack of standardized definitions for restrictive or liberal fluid regimens, with challenges related to patient selection. Goal-directed fluid therapy is suggested for more complex cases. Critical…
Researchers found that despite recommendations for extended thromboprophylaxis, only 63% of patients received appropriate treatment in the inpatient setting. Additionally, only 2% of patients received recommended prophylaxis post-discharge, resulting in no thromboembolic events. Adherence to risk-guided prophylaxis led to decreased rates of venous thromboembolism without…
Colorectal cancer (CRC) risk after resection of low- and high-risk adenomas was investigated in a fit-based CRC screening program. The study included 87,248 post-fit+ colonoscopies and found that patients with low-risk adenomas did not have an increased CRC incidence compared to the fit+/colonoscopy negative group.…
Robotic surgery has been shown to significantly reduce the occurrence and severity of low anterior resection syndrome (LARS) in patients with lower rectal cancer. In a study involving 342 patients, the incidence of major LARS was significantly lower in the robotic surgery group compared to…
