Comprehensive analysis of 311 patients with locally advanced rectal cancer revealed a 26.4% pathological complete response rate and significant downstaging in 75.2% of cases. At a median follow-up of 36 months, local and distant recurrence rates were 5.7% and 12.5%, respectively. The five-year cancer-specific survival and disease-free survival rates reached 88.8% and 80.5%, with downstaged […]

A groundbreaking training simulator, COLOMASTER, has been developed for laparoscopic right hemicolectomy. This innovative device eschews animal tissue, utilizing dry polyester fibers and hydrogel to emulate human anatomy and facilitate realistic surgical techniques. Surgeons can practice complete mesocolic excision, central vascular ligation, and intracorporeal anastomosis, critical skills for improving patient outcomes. With its focus on […]

A novel terminal ileal vein (TIV) approach enhances identification of the superior mesenteric vein during laparoscopic right hemicolectomy, leading to improved surgical outcomes. In a study of 196 patients, the TIV method resulted in significantly shorter operation times (186 vs. 210 minutes) and reduced intraoperative blood loss (50 vs. 70 ml). Patients also experienced shorter […]

Application of glubran 2, a cyanoacrylate-based sealant, in ileocolic anastomoses during right colectomy significantly reduced anastomotic leak (AL) rates from 6.18% to 1.85% (p

A narrative review identifies key clinical contexts where shared decision-making (SDM) can enhance treatment outcomes for rectal cancer patients. It emphasizes organ preservation, sphincter preservation, and tailored stoma policies, highlighting the importance of balancing oncological safety with quality of life. Strategies like “watch-and-wait” and tailored stoma closure innovations have shown promise in minimizing complications. By […]

A recent analysis of 22,312 patients shows that same-day (0.9%) and short-stay (8.2%) stoma closure protocols significantly reduce overall morbidity compared to traditional inpatient stays (90.9%)—11.8%. Both expedited discharge methods demonstrate comparable safety outcomes, with the inpatient group experiencing higher reoperation rates. Despite evidence supporting these approaches, their adoption remains limited, highlighting potential for improved […]

A nationwide study reveals that 15% of patients with non-metastasized rectal cancer successfully utilized a watch and wait strategy after neoadjuvant treatment. Among those treated with chemoradiotherapy, 21% achieved favorable results, compared to just 7% for short-course radiotherapy. Organ preservation rates improved to 17% when local excisions were included. Data indicate better baseline performance and […]

A new clinical prediction model offers reliable assessment for anastomotic leakage (AL) in rectal cancer surgery, based on a study of 3,765 patients. The model identified key risk factors, including gender, diabetes, preoperative chemoradiotherapy, and surgical parameters. With area under the curve (AUC) values of 0.818 and 0.815 for internal validation, and consistent calibration results, […]

A recent study identified ten key genes associated with colorectal cancer (CRC) stemness, revealing their correlation with disease-free and progression-free survival. Using a machine learning model, researchers found that higher mRNA expression-based stemness indexes (mrnasi) correlated with improved clinical outcomes. Notably, CRC samples with lower mrnasi exhibited worse survival rates. This research highlights the potential […]