Subscribe free

Newsletter

Intestine and Lower Gastrointestinal Tract

Every new paper in this field, in your inbox.

FreeNo spamOne-click unsubscribe
Ann Surg6 Dec 2023

Total Neoadjuvant Therapy for Rectal Cancer: Impact on Surgical Outcomes and Pathology

In a meta-analysis of 11 randomized controlled trials involving 3,185 rectal cancer patients, researchers compared total neoadjuvant therapy (TNT) to standard long course chemoradiotherapy (LCRT). TNT did not significantly differ in mortality or major complications but increased the risk of breached total mesorectal excision (TME).…

Intestine and Lower Gastrointestinal Tract5 Dec 2023

Optimal Surgical Approach for Small Bowel Neuroendocrine Tumors

In addressing the surge in small bowel neuroendocrine tumors (SB-NETs), this study underscores surgery's pivotal role. Emphasizing multifocal assessment and mesenteric-sparing strategies, it delineates eight systematic steps for surgical planning. While stressing the necessity of achieving oncological control, some controversies persist, notably regarding resection in…

BMC Surg5 Dec 2023

Optimizing Surgical Approach in Synchronous Colorectal Liver Metastases

Analyzing data from 976 patients with synchronous colorectal liver metastases, researchers compared simultaneous and staged resections. Simultaneous resection, beneficial for low to moderate tumor burden and node-negative right-sided primary tumors, showed increased complications in high tumor burden cases. Staged resection demonstrated better outcomes for patients…

J Gastroenterol5 Dec 2023

Surgery in Acute Lower Gastrointestinal Bleeding

In a cohort study of 10,342 acute lower gastrointestinal bleeding (ALGIB) cases, surgery was performed in 1.3%. Colonoscopy (87.7%) and endoscopic hemostasis (26.7%) were common. Surgery indications included diverticular bleeding (24%) and colorectal cancer (22%). Sixty-four percent were for severe refractory bleeding. Postoperative rebleeding rates…

BMC Surg4 Dec 2023

Optimizing Rectal Cancer Surgery: Benefits of Transanal Total Mesorectal Excision

In a meta-analysis of four randomized controlled trials (1,339 patients), researchers compared laparoscopic total mesorectal excision (TME) with and without transanal dissection for lower rectal cancers. Those undergoing laparoscopic TME with transanal dissection exhibited lower conversion rates, a higher likelihood of achieving complete TME, and…

Gastrointest Endosc3 Dec 2023

Innovative Closure Strategy for Rectal Defects Post-Endoscopic Submucosal Dissection

Researchers introduced an endoscopic hand-suturing with clips strategy (EHS-clips) for closing rectal defects after endoscopic submucosal dissection (ESD) or ESD with myectomy. All 49 defects achieved complete closure, with 71.4% through EHS alone and 28.6% with additional clips. Zero cases experienced delayed bleeding. Sustained closure…