Ann Surg7 Dec 2023
A randomized controlled trial evaluated the effectiveness of a postdischarge mobile app in reducing 30-day readmissions and improving patient-reported outcomes after elective colorectal surgery. The app did not significantly reduce readmissions or emergency room visits, but it led to significant improvements in patient satisfaction, well-being,…
Ann Surg6 Dec 2023
In a meta-analysis of 11 randomized controlled trials involving 3,185 rectal cancer patients, researchers compared total neoadjuvant therapy (TNT) to standard long course chemoradiotherapy (LCRT). TNT did not significantly differ in mortality or major complications but increased the risk of breached total mesorectal excision (TME).…
HPB & Spleen6 Dec 2023
Analyzing 72,376 patients with colorectal liver metastases (CRLM) from the National Cancer Database, researchers found that liver-only CRLM patients undergoing perioperative chemotherapy had a superior median overall survival (OS) of 44.7 months. Resection of both primary and metastatic sites also correlated with better OS (38.9…
Intestine and Lower Gastrointestinal Tract6 Dec 2023
Investigating the combination of pelvic exenterations and cytoreductions in T4 rectal cancers with peritoneal metastasis, a study on 39 patients (median age 35) revealed safety in terms of morbidity (18% major complications). Although achieving CC-0 in 97.4%, hyperthermic intraperitoneal chemotherapy was administered to 15 patients.…
Intestine and Lower Gastrointestinal Tract5 Dec 2023
In addressing the surge in small bowel neuroendocrine tumors (SB-NETs), this study underscores surgery's pivotal role. Emphasizing multifocal assessment and mesenteric-sparing strategies, it delineates eight systematic steps for surgical planning. While stressing the necessity of achieving oncological control, some controversies persist, notably regarding resection in…
BMC Surg5 Dec 2023
Analyzing data from 976 patients with synchronous colorectal liver metastases, researchers compared simultaneous and staged resections. Simultaneous resection, beneficial for low to moderate tumor burden and node-negative right-sided primary tumors, showed increased complications in high tumor burden cases. Staged resection demonstrated better outcomes for patients…
J Gastroenterol5 Dec 2023
In a cohort study of 10,342 acute lower gastrointestinal bleeding (ALGIB) cases, surgery was performed in 1.3%. Colonoscopy (87.7%) and endoscopic hemostasis (26.7%) were common. Surgery indications included diverticular bleeding (24%) and colorectal cancer (22%). Sixty-four percent were for severe refractory bleeding. Postoperative rebleeding rates…
BMC Surg4 Dec 2023
In a meta-analysis of four randomized controlled trials (1,339 patients), researchers compared laparoscopic total mesorectal excision (TME) with and without transanal dissection for lower rectal cancers. Those undergoing laparoscopic TME with transanal dissection exhibited lower conversion rates, a higher likelihood of achieving complete TME, and…
Gastrointest Endosc3 Dec 2023
Researchers introduced an endoscopic hand-suturing with clips strategy (EHS-clips) for closing rectal defects after endoscopic submucosal dissection (ESD) or ESD with myectomy. All 49 defects achieved complete closure, with 71.4% through EHS alone and 28.6% with additional clips. Zero cases experienced delayed bleeding. Sustained closure…
Ann Surg2 Dec 2023
In the No.2-Trial, comparing sacral neuromodulation (SNM) to personalized conservative treatment (PCT) for refractory idiopathic slow-transit constipation, SNM demonstrated significant success (53.7%) compared to PCT (3.8%) after six months. SNM patients reported lower constipation severity and fatigue, along with improved quality of life. Serious adverse…