A multicenter prospective study aims to evaluate a clinical pathway using routine bedside endoscopy for early detection of anastomotic leakage (AL) following colorectal surgery. Researchers hypothesize that this approach will reduce the median time for AL diagnosis from 15 to 5 days. The pathway includes endoscopic inspection and guided CT scans within the first weeks […]
Category: Intestine and Lower Gastrointestinal Tract
Seventeen lymph nodes optimally predict survival in mucinous adenocarcinoma
A multicenter study analyzed lymph node evaluations in colorectal mucinous adenocarcinoma (MAC) and established that examining at least 17 lymph nodes (ELNs) significantly correlates with improved survival rates. Data from Chinese and SEER cohorts showed a consistent median ELN count of 17, with higher counts reducing mortality risks for MAC patients. This finding challenges the […]
Treatment adjustments significantly enhance endoscopic prognosis in Crohn’s disease
In a cohort of 199 Crohn’s disease patients with postoperative anastomotic lesions, treatment adjustments yielded notable improvements in endoscopic outcomes. Specifically, strategies such as biologics switching and biologic optimization led to marked mucosal healing and ulcer improvement. Switching from non-biologics to biologics resulted in superior endoscopic results, while optimization of biologics enhanced outcomes for patients […]
Preoperative factors influence risk of permanent stoma after surgery
A study involving 639 rectal cancer patients identified key preoperative risk factors for permanent stoma post-sphincter-preserving surgery. Notably, 11.9% of patients developed a permanent stoma within two years. Factors such as male sex, tumor height, and the presence of synchronous liver or lung metastases were linked to a higher likelihood of stoma permanence. Furthermore, patients […]
Identifying key signs of small bowel strangulation improves diagnosis
Findings indicate that mesenteric edema and abnormal bowel wall thickening serve as sensitive and specific indicators for both non-necrotic and necrotic small bowel strangulation (SBS). In a study involving 141 SBS patients, these indicators were significantly less frequent in cases of simple bowel obstruction. Notably, bowel hypo-enhancement was present in only half of the non-necrotic […]
Robotic-assisted surgeries improve outcomes in rectal resections.
A multicenter real-world study analyzed rectal resections in 829 patients, revealing notable outcomes for robotic-assisted surgeries. This group experienced shorter hospital stays, less blood loss, and fewer postoperative complications compared to laparoscopic and open surgery techniques, while also achieving lower rates of positive circumferential resection margins. However, robotic-assisted surgeries required longer operating times. Early administration […]
Affordable and Realistic Surgical Training Models Developed
Surgical training is enhanced by newly developed low-cost, high-fidelity skin and intestine surrogates. Utilizing 3D printing and readily available silicone materials, these models significantly improve biomechanical accuracy compared to industry standards. Feedback from surgical residents at the University of Missouri School of Medicine highlights their effectiveness, with a cost reduction of over 90% compared to […]
Osteopenia and osteosarcopenia forecast outcomes in gastrointestinal cancers.
A systematic review identified osteopenia as a significant prognostic factor for overall survival (OS) and recurrence-free survival (RFS) in gastrointestinal cancer patients, with pooled hazard ratios of 2.20 and 2.15, respectively. Patients with osteosarcopenia faced threefold higher mortality and increased recurrence risk, highlighted by pooled hazard ratios of 2.96 and 2.75. These findings underscore the […]
Nomograms effectively predict long-term survival in metastatic colon cancer.
A population-based analysis of 6,857 patients with de novo metastatic colon cancer developed a nomogram to predict overall survival (OS) and cancer-specific survival (CSS). Key prognostic factors included histological grade, age, cancer stage, metastasis presence, perineural invasion, carcinoembryonic antigen levels, chemotherapy, and surgery. The nomogram showed a promising concordance index of 0.72, allowing for stratification […]
Blood glucose regulation significantly improves survival in Fournier’s gangrene
Elevated blood glucose at admission is linked to increased mortality in Fournier’s gangrene patients. A study of 36 patients indicated a 16.7% mortality rate, with diabetes common in 61.1% of cases. The optimal glucose cut-off of 186.5 mg/dl provided 83.3% sensitivity and specificity for predicting mortality. While existing scoring systems like LRINEC and CUPI showed […]