Intraoperative blood loss (IBL) ratios were found to predict local recurrence after curative resection in stage I-III colorectal cancer patients. Higher IBL ratios correlated with a greater risk of early local recurrence within two years post-surgery. Multivariate analysis indicated that factors such as anastomotic leakage and tumor characteristics, including rectal cancer and poorly differentiated histology, […]
Category: Intestine and Lower Gastrointestinal Tract
Thermal ablation shows comparable efficacy with better safety for colorectal liver metastases.
A multi-center study of 303 patients with colorectal liver metastases revealed no significant difference in early recurrence patterns after resection versus thermal ablation. Both treatments showed similar 6-month recurrence-free survival rates; however, thermal ablation demonstrated a lower incidence of serious complications and shorter hospitalization. Key risk factors for early recurrence were identified, including the diameter […]
Elevated preoperative tumor markers affect survival in cancer patients
Elevated preoperative levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), and cancer antigen 125 (CA125) in colorectal cancer patients with peritoneal metastases significantly influence overall survival. In a study of 204 patients, the presence of high CA19-9 and CA125 was linked to poorer outcomes, with hazard ratios of 2.7 and 2.2, respectively. Histopathological features […]
Autologous flap-supported stomas improve patient outcomes significantly
A comparative study of autologous flap-supported loop stomas revealed significant benefits over traditional rod-supported loop stomas. The intervention group showed lower short-term complication rates, particularly in peristomal dermatitis and stoma leakage, alongside reduced stoma appliance replacement frequency and costs. Additionally, operating times and blood loss during closure surgery were also lower for the intervention group. […]
Colonic J-Pouch Reconstruction Improves Quality of Life Post-Surgery
A prospective cohort study involving 66 patients with ultra-low rectal cancer revealed that colonic j-pouch reconstruction significantly enhances bowel function and quality of life compared to direct anastomosis. At all postoperative intervals (1, 3, and 6 months), patients who received the j-pouch exhibited superior LARS and FIQL scores. Both approaches showed similar postoperative complication rates, […]
Individualized strategies improve survival in metastatic rectal cancer
An extent-based tailored strategy for managing rectal cancer with synchronous resectable liver metastases achieved an 82% complete resection rate in a study involving 83 patients. Over a median follow-up of 43 months, the median overall survival reached 58 months, with one- and three-year survival rates at 94% and 73%, respectively. Multivariate analysis highlighted complete resection […]
Stapling anastomosis is increasingly preferred for colectomy.
Analysis of 232,155 colectomy cases revealed that stapling anastomosis (SA) is favored over hand-sewn anastomosis (HA), with usage rising from 80% in 2015 to 85% in 2021. The study, using propensity score matching, indicated a higher reoperation risk in the HA group (1.27%) compared to the SA group (0.93%; risk ratio 1.36). Conversely, SA was […]
Older patients face higher risks in minimally invasive surgeries
A multicenter study of 7,303 patients revealed that octogenarians undergoing laparoscopic or robot-assisted colorectal surgeries exhibit significantly higher postoperative complication rates compared to younger counterparts. Specifically, patients aged 80 and above had increased comorbidities and elevated ASA and ECOG-PS scores, indicating greater surgical risks. Findings suggest that minimizing operation time and controlling blood loss are […]
High risk of surgery in complicated chronic diverticular disease
A nationwide study covering Denmark from 1996 to 2020 evaluated 33,951 patients with chronic diverticular disease and found a 5-year cumulative incidence of surgical intervention at 13.9%—9.8% elective and 4.2% emergency. Complicated cases presented a three- to six-fold increased likelihood of surgery compared to uncomplicated cases. Younger patients and those with more emergency admissions faced […]
Standardized training for colorectal liver metastases established
A new structured guide addressing colorectal liver metastases (CRLM) fills a vital gap in surgical oncology education. By updating the European Society of Surgical Oncology’s curriculum, it provides essential information on epidemiology, staging, and treatment strategies. Researchers conducted a thorough literature review, focusing on recent guidelines and studies, to support hepatobiliary surgeons and oncologists. This […]