Surg Endosc11 May 2025
A deep learning computer vision model demonstrated precise real-time identification of the left ureter during laparoscopic sigmoidectomy, achieving a mean average precision of 0.92. Key evaluation metrics, including precision, recall, and dice coefficient, reached impressive values of 0.94, 0.88, and 0.90, respectively. Operating at 32…
Scand J Gastroenterol10 May 2025
A 22-year retrospective study of 1,197 ulcerative colitis patients reveals that the introduction of biological agents has drastically cut colectomy rates from 12% to 2%. This major finding underscores the importance of achieving mucosal remission and maintaining low CRP levels to further reduce the necessity…
BMC Gastroenterol10 May 2025
Active wound dressings significantly reduce postoperative pain and accelerate wound healing in patients following anorectal surgery. In a study with 110 participants, pain scores were notably lower in those receiving active dressings on days 1, 3, and 7 post-operation. Furthermore, the wound healing rates were…
J Chin Med Assoc10 May 2025
Findings indicate that age (≥45 years), male sex, and certain baseline colonoscopic findings are critical predictors of metachronous advanced colorectal adenomas post-polypectomy. Among 2,013 patients, those with multiple small or advanced adenomas showed significantly higher risks, with odds ratios of 3.27 and 5.41, respectively. These…
Gastrointest Endosc8 May 2025
Findings indicate that conventional endoscopic resection techniques can safely and effectively handle previously partially resected colorectal polyps. Out of 220 such lesions, all were successfully resected with similar recurrence rates (8.2%) compared to lesions without prior resection (7.8%). Notably, previously resected lesions required more advanced…
N Engl J Med7 May 2025
In a phase 2 study involving 117 patients with early-stage mismatch repair-deficient solid tumors, neoadjuvant dostarlimab led to high rates of clinical complete responses. Specifically, all patients in cohort 1 with locally advanced rectal cancer opted for nonoperative management. Among cohort 2, 35 out of…
Therap Adv Gastroenterol7 May 2025
In a study analyzing 1,259 colorectal polyps from 1,025 patients, complete closure using titanium clips significantly reduced the incidence of delayed postpolypectomy bleeding (DPPB) to 3.6%. Factors influencing DPPB included male gender and polyp size, both immutable, while incomplete closure presented a higher risk. Logistic…
Intestine and Lower Gastrointestinal Tract4 May 2025
Colorectal cancer (CRC) is increasingly prevalent in Ghana, often diagnosed at younger ages and later stages, which leads to poorer survival rates. Key challenges identified include limited healthcare resources, inadequate screening, and sociocultural barriers that affect treatment access. The study emphasizes the need for enhanced…
J Gastroenterol Hepatol4 May 2025
The developed AI-assisted system significantly improves the detection and localization of colorectal polyps during colonoscopy. Out of five CNN models tested, EfficientNetV2 excelled, achieving an accuracy of 93.3% and a specificity of 94.6% on the test set. The system's performance metrics, including a high AUC…
Ann Surg Oncol3 May 2025
Evaluation of total metastases volume (TMV) and relative volume reduction (RVR) reveals their superior predictive ability over established clinical risk scores (CRS) for colorectal liver metastases post-neoadjuvant chemotherapy. Patients with TMV below 29.5 ml before and 7.5 ml after therapy had significantly longer progression-free survival…