High-volume centers in the USA saw positive results with Transanal Total Mesorectal Excision (TaTME) for rectal cancer. The study of 391 patients revealed low rates of local recurrence, high completion rates of TME specimens, and promising 3-year overall survival. These findings support the oncologic safety and perioperative benefits of TaTME when conducted by skilled surgeons […]
Category: Intestine and Lower Gastrointestinal Tract
Left-Sided Colon Cancer Shows Better Survival Than Rectal Cancer Post-Hepatic Metastasectomy
Survival outcomes differed between left-sided colon and middle/low rectal cancer post-colorectal hepatic metastasectomy. Patients with left-sided colon cancer exhibited significantly better overall survival (OS) than those with middle/low rectal cancer, especially in the subgroup analysis of ras mutations. The study suggests that middle/low rectal cancer should not be grouped together with left-sided colon cancer in […]
Colorectal Carcinoma In Situ Can Metastasize and Recur
Colorectal carcinoma in situ can metastasize to lymph nodes and recur, challenging previous assumptions. Among 1069 patients, 0.46% experienced regional lymph node metastasis or recurrence, with cases identified during or after primary surgery. Distant metastases were also observed, emphasizing the need for careful assessment at diagnosis. This study highlights the importance of recognizing potential metastasis […]
Prognostic Value of Lymphocyte-to-C-Reactive Protein Ratio in Fournier’s Gangrene
Younger patients with low lymphocyte-to-C-reactive protein ratio had better survival rates in Fournier’s gangrene. Higher hospital costs correlate with increased mortality risk. The Fournier’s Gangrene Severity Index, lymphocyte-to-C-reactive protein ratio, and neutrophil-lymphocyte ratio were effective at predicting patient outcomes. A low lymphocyte-to-C-reactive protein ratio was identified as a potential marker for assessing mortality and disease […]
Diet and Antibiotics Impact Anastomotic Healing in Mice
Mouse study reveals that a high-fat-low-fiber diet leads to poor survival, weight loss, and reduced microbiome diversity compared to a low-fat-high-fiber diet. Pre-operative antibiotics enhance anastomotic healing by reducing enterococcus faecalis growth and improving collagen levels. Dietary fiber promotes post-operative recovery and microbiome biodiversity, highlighting the importance of diet and antibiotics in gut health and […]
Machine Learning Model for Prediction of Permanent Stoma after Anterior Resection of Rectal Cancer
Retrospective study develops a machine learning model to predict permanent stoma formation post rectal cancer surgery. Utilizing support vector machine algorithm, the model shows high accuracy (AUC: 0.854) in training, testing, and external validation sets, aiding in preoperative patient stratification and personalized treatment plans. Results offer a practical tool for clinicians to enhance patient outcomes […]
Disparities in Postoperative Outcomes Among Patients with Inflammatory Bowel Disease
Study reveals black patients with inflammatory bowel disease have higher rates of postoperative infections, morbidity, mortality, and longer hospital stays compared to white or Hispanic patients, despite having fewer comorbidities. This highlights significant racial disparities in postoperative outcomes, emphasizing the need to address social determinants of health to improve equity in care for all patients […]
Radiotherapy, Diverting Stoma, Anastomotic Leakage, and Anastomotic Distance are Key Predictors for Anastomotic Stricture after Rectal Cancer Surgery
Developed predictive model using a nomogram to predict anastomotic stricture post anterior resection for rectal cancer. Key predictors include radiotherapy, diverting stoma, anastomotic leakage, and anastomotic distance. The model demonstrated high accuracy with AUC of 0.889 for training set and 0.930 for validation set. Nomogram has clinical value in predicting anastomotic stricture, aiding clinicians in […]
Laparoscopic Surgery Improves Outcomes for Colorectal Cancer
Comparing laparoscopic and open surgery for colorectal cancer, researchers found significant advantages with minimally invasive surgery, including shorter hospital stay, lower medical complications, and improved survival. Both approaches showed similar pathological outcomes in terms of lymph nodes and margins. Laparoscopic surgery, when performed by skilled surgeons, is oncologically safe and is increasingly becoming the standard […]
Advantages of Dilip’s Transmucosal Internal Sphincterotomy for Fissure-in-Ano
Dilip’s Transmucosal Internal Sphincterotomy (TMIS) simplifies the lateral internal sphincterotomy (LIS) process, offering a less invasive and more precise method for treating fissure-in-ano. With a median operative time of 7 minutes, low post-operative pain, and minimal risk of complications, TMIS presents significant benefits over traditional LIS. The innovation provides a safer, more accessible option for […]