Researchers examined the outcomes of sleeve gastrectomy (SG) in patients with familial aggregation of obesity (FAO) compared to those with sporadic obesity (SO). The study, involving 193 patients, found no significant differences in baseline characteristics or short-term postoperative weight loss between FAO and SO groups. However, by the two-year mark, patients with FAO had a […]
Category: Metabolic and Bariatric Surgery
Smaller Gastrojejunostomy Diameters Linked to Enhanced Weight Loss in Laparoscopic Gastric Bypass
Researchers reviewed the impact of gastrojejunostomy (GJ) anastomosis diameter on weight loss outcomes after laparoscopic Roux-en-Y gastric bypass (RYGB). In the systematic review, including six studies with varying GJ diameters and follow-up durations of 1-5 years, smaller GJ diameters generally led to greater short-to-medium-term weight loss. However, complications like stenosis increased with smaller diameters beyond […]
Endoscopic bariatric and metabolic therapies for obesity: ASGE-ESGE guideline
The joint American Society for Gastrointestinal Endoscopy-European Society of Gastrointestinal Endoscopy (ASGE-ESGE) guideline provides evidence-based recommendations for endoscopic bariatric and metabolic therapies (EBMTs) in treating obesity. Using the GRADE framework, the guideline evaluates the efficacy and safety of EBMT devices and procedures with CE Mark or FDA clearance/approval. It recommends EBMTs plus lifestyle modification for […]
Over-the-Scope Clips Show Higher Success Rates for Bariatric Surgery Leaks
A meta-analysis of five studies found that the pooled proportion of successful closure with over-the-scope clips (OTSC) for leaks and fistulae following bariatric surgery was 81.1% (95% CI 67.3 to 91.7). Observational reports suggest that patients managed with OTSC had higher rates of defect healing compared to those treated with endoscopic suturing. Larger controlled studies […]
Shorter Operative Times and Hospital Stays with 3D Laparoscopic Bariatric Surgery Compared to 2D.
Six studies with 629 patients compared 2D and 3D laparoscopic bariatric surgery. 3D laparoscopy showed significantly shorter operative times and hospital stays during gastric bypass and sleeve gastrectomy procedures. It also indicated potential benefits in preventing complications. Surgeons may find 3D laparoscopy advantageous in bariatric surgery despite limited evidence. Review by Peltrini R, Esposito MD […]
Medium-Term Outcomes of One Anastomosis Gastric Bypass in Australia
This case series of 1000 patients undergoing one anastomosis gastric bypass in Australia showed a mean total weight loss of 33.6% with 74% achieving type 2 diabetes remission at 1-year post-op. Complication rates, including bile reflux and marginal ulceration, were low, with no cases of internal herniation reported. Results support the efficacy and safety of […]
Incidence of Venous Thromboembolic Events After Metabolic and Bariatric Surgery
Systematic review/meta-analysis of 87 studies and 2,731,797 patients shows low cumulative incidence of VTE after metabolic and bariatric surgery. In-hospital VTE rates were 0.15%, increasing to 0.78% at 12 months. Open approach surgeries had higher incidence than laparoscopic. 60% of VTE occurred within first month post-discharge. North American and earlier studies had higher incidence. Extended […]
Positive Effects of Laparoscopic Sleeve Gastrectomy
Significant weight loss and improvements in body composition and metabolic biomarkers were observed in obese patients after laparoscopic sleeve gastrectomy. These positive effects were seen regardless of the presence of metabolic syndrome. Visceral fat area and liver fat were notably reduced, indicating the effectiveness of this surgical intervention in improving health outcomes. Journal Article by […]
Gastrin Orchestrates Glucose Regulation Post-Sleeve Gastrectomy
Gastrin plays a central role in glucose improvement after sleeve gastrectomy (SG). SG induces a medium-term elevation of the insulin response and plasma gastrin levels, with long-term depletion of the insulin response and elevated oral glucose tolerance test results. Gastrin antagonists, like netazepide, prevent these effects. This study highlights the dual effects of gastrin on […]
Impact of Preoperative Comorbidities on %EBWL After Bariatric Surgery
Patients with higher baseline BMI, diabetes mellitus, hypothyroidism, and those undergoing laparoscopic sleeve gastrectomy may experience lower %EBWL in the first year post-bariatric surgery. Anxiety, depression, and obstructive sleep apnea were not significantly associated with %EBWL. This study highlights the need for tighter control of certain comorbidities to optimize weight loss outcomes after bariatric surgery. […]