Newsletter
Best Papers in General Surgery
The five that matter, every day.
Hypoalbuminemia and significant intraoperative blood loss elevate anastomotic leakage risk after laparoscopic radical gastrectomy. Conversely, total gastrectomy offers protection against this complication. Among patients post-distal gastrectomy, smoking, pyloric obstruction, and Roux-en-Y anastomosis correlate with increased gastroparesis syndrome risk. This robust analysis of 3,779 patients clarifies…
A newly developed nomogram effectively predicts overall survival for hepatocellular carcinoma (HCC) patients with major vascular invasion. Analyzing data from 2,211 patients, key survival factors include tumor size, N stage, metastases, and treatment modalities. The model demonstrates robust predictive accuracy with c-index values around 0.72–0.73…
A meta-analysis of 38,647 gastric bypass patients across 27 countries reveals robotic Roux-en-Y gastric bypass (rrygb) requires longer surgical time but offers improved intraoperative safety compared to laparoscopic Roux-en-Y (lrygb). Despite a significant increase in robotic surgeries from 0.2% to 5.7% over 25 years, both…
Neoadjuvant chemotherapy without radiation significantly reduces anastomotic leaks, diverting ostomy use, and ostomy non-reversal in locally advanced rectal cancer patients. In a meta-analysis of four randomized controlled trials, chemotherapy was found equivalent or non-inferior to chemoradiation for oncologic outcomes. However, critical surgical outcomes remain inadequately…
Patients adhering to an enhanced recovery pathway (ERP) during colorectal cancer surgery saw a 31% reduction in overall mortality compared to those with low adherence. In a study involving 2,865 patients, those in the highest adherence quartile (≥80.8%) experienced a significant drop in death risk,…
New endoscopic methods, EDGE and EDEE, revolutionize access to the biliary system for patients with surgically altered anatomy. These techniques facilitate minimally invasive procedures, significantly lowering morbidity rates while maintaining high success rates. By using lumen-apposing metal stents, they improve safety profiles and expand treatment…
Quality of life after emergency abdominal surgery improves significantly for survivors over time. Initial post-operative EQ-5D-3L utility scores averaged just 0.21, but soared to 0.74 within three to eight months. Key early determinants include patient's sex and preoperative risk levels, while longer-term outcomes are influenced…
Early drainage with lavage and delayed step-up surgery demonstrate significant survival benefits in necrotizing pancreatitis, decreasing mortality and complications. In contrast, delayed video-assisted surgery leads to higher mortality rates. No significant differences between early and delayed intervention approaches were found. Tailoring treatment based on individual…
Postoperative antibiotic prophylaxis (ppa) significantly lowers the incidence of liver-specific surgical site infections (liver-ssi) in patients undergoing simultaneous liver and colorectal resections. In a cohort of 250 patients, those receiving ppa experienced a liver-ssi rate of 11% versus 29.3% in the control group (p
Patients with inflammatory bowel disease (IBD) undergoing colorectal cancer surgery face a significantly elevated risk of venous thromboembolism (VTE) compared with those without IBD. The analysis highlights VTE as a critical postoperative complication in this population, underscoring the need for heightened vigilance and tailored thromboprophylaxis…
