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Best Papers in General Surgery
The five that matter, every day.
In a pivotal 5-year follow-up of the FUGES-012 trial, patients who underwent indocyanine green (ICG) fluorescence-guided laparoscopic lymphadenectomy for gastric cancer exhibited significantly improved overall survival and disease-free survival compared to the non-ICG cohort. The ICG group also showed fewer recurrences, with a notable reduction…
Dynamic prognostic models for colorectal cancer with liver metastases significantly enhance survival predictions by integrating longitudinal laboratory markers. In a cohort of 976 patients, the most effective model outperformed static approaches, achieving area under the curve (AUC) values of 0.850 for five-year progression-free survival and…
A phase II trial aims to assess the effectiveness of indocyanine green (ICG) fluorescence-guided lymph node mapping in determining bowel resection margins for patients with colon cancer. By tailoring lymph node dissection based on individual anatomy, the approach seeks to balance extensive dissection and potential…
A 6-week multimodal prehabilitation program significantly slashed postoperative morbidity in patients with sarcopenia undergoing major hepatectomy. The prehabilitation group experienced a mere 13.3% complication rate compared to 50% in the standard care arm, translating to a 36.7% absolute risk reduction. All major complications occurred in…
Salivary pepsin testing objectively tracks reflux trajectories in post-esophagectomy patients. The study identifies redundancy of conduit as a significant risk factor for increased reflux, while maintaining a semi-fowler position and pre-sleep fasting for at least two hours offers protective benefits. These findings highlight essential modifiable…
The robotic NICE procedure delivers superior cost-effectiveness in left-sided colorectal resections, showing a median direct cost of $9,946—well below laparoscopic ($16,389), robotic ($14,473), and open surgery ($10,427). Total costs mirror this trend, with NICE at $22,263, contrasted with $29,324 for laparoscopic, $32,908 for robotic, and…
A mobile app for bowel preparation training outperformed standard instructions in ensuring compliance and quality among colonoscopy patients. In a trial of 160 adults, those using the app achieved a 94.9% adequacy rate compared to 83.8% for the control group. Compliance with dietary protocols also…
Log odds of positive lymph nodes (lodds) and positive lymph node ratio (lnr) demonstrate superior predictive capabilities for survival in gastric signet ring cell carcinoma (gsrc) patients compared to the traditional AJCC n-category. Multivariate analysis reveals both lodds and lnr as significant prognostic factors, with…
Conversion therapy (CT) significantly improves overall and progression-free survival in patients with locally advanced intrahepatic cholangiocarcinoma (LA-ICCA). In a retrospective analysis of 115 patients, median overall survival reached 45.53 months and progression-free survival was 18.23 months post-propensity score matching, both superior to systemic therapy (ST)…
A cohort of 414 older adults undergoing major elective surgery revealed striking results: those classified as overweight (BMI 25.0-29.9) had an astonishingly low 30-day all-cause mortality rate of just 0.8%. In stark contrast, normal-weight patients faced an 18.8% mortality rate, while underweight individuals experienced a…
