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General Surgery

Best Papers in General Surgery

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Ann Surg Oncol29 Aug 2025

Social Vulnerability Tied to Higher Postoperative Complications in Cancer Surgery

Among 34,253 patients undergoing hepatopancreatobiliary cancer surgery, high allostatic load (AL) strongly correlated with increased postoperative risks. Those in socioeconomically vulnerable areas faced a 44% higher likelihood of severe complications and an 85% increased chance of failure to rescue. A significant twofold increase in 30-day…

BMC Surg29 Aug 2025

Endoloop Laparoscopic Appendectomy Slashes Carbon Emissions by 81%

The endoloop technique for laparoscopic appendectomy delivers a staggering 81% reduction in greenhouse gas emissions compared to stapler methods. It also significantly lowers human health costs related to environmental damage—six to ten times less than alternatives. Most emissions stem from raw material extraction and production,…

HPB & Spleen29 Aug 2025

Interventional Endoscopy Revolutionizes Treatment for Complex Gastroenterological Issues

Endoscopic ultrasonography (EUS) has transformed from a diagnostic tool to a crucial therapeutic method. Today, EUS-guided procedures are standard for managing symptomatic pancreatic fluid collections and offer alternatives for high-risk surgical patients with acute cholecystitis. It also provides solutions for biliary obstructions after failed ERCP.…

Medicine (Baltimore)29 Aug 2025

CT-derived extracellular volume improves colorectal cancer differentiation predictions

CT-derived extracellular volume fraction (ct-ecv) significantly correlates with histological grading in colorectal cancer. In a study of 200 patients, ct-ecv, alongside serological markers like CEA and NLR, effectively predicted poorly differentiated tumors. The combination of ct-ecv with NLR and tumor markers yielded an impressive AUC…

Intestine and Lower Gastrointestinal Tract28 Aug 2025

New insights on hemorrhoidal disease treatments: effectiveness and limitations

Hemorrhoidal disease impacts 10 million Americans, causing bleeding, pain, and discomfort. First-line treatments like increased fiber and water intake, along with phlebotonics, often fail, leading to 80% symptom recurrence. Office-based interventions are vital for grades I to III; rubber band ligation offers 89% short-term relief,…

Am J Gastroenterol28 Aug 2025

Postcolonoscopy Colorectal Cancers Reveal Distinct Molecular Patterns

Postcolonoscopy colorectal cancers (pccrcs) show higher rates of microsatellite instability, CIMP, and BRAF mutations compared to sporadic cases, alongside a greater presence of proximal lesions. Although 5-year survival rates are similar between pccrcs and sporadic colorectal cancers, pccrcs fare significantly worse than cancers detected via…

BMC Surg28 Aug 2025

Longer Postoperative Stays Correlate with Higher Unplanned Readmission Risks

Increasing postoperative length of stay raises the likelihood of unplanned readmissions among surgical patients. In a comprehensive study of over 3 million individuals, those staying 3-10 days post-surgery showed significantly higher odds of readmission compared to those discharged within 0-2 days. This trend persisted across…

BMC Surg28 Aug 2025

Combined APACHE II and lactate levels predict post-op mortality in high-risk patients

For patients facing emergency laparotomy due to gastrointestinal perforation peritonitis, integrating serial APACHE II scores and serum lactate levels significantly enhances mortality prediction. The combination shows an impressive 85% sensitivity and 82% specificity for 30-day postoperative death, outperforming individual markers. With a mortality rate of…

HPB & Spleen28 Aug 2025

Early Exercise Speeds Recovery for Pancreatic Cancer Surgery Patients

Early progressive resistance exercise after pancreaticoduodenectomy accelerates recovery, significantly reducing time to first water intake, food intake, ambulation, and length of hospital stay. With 80 patients involved, those engaging in structured exercise reported faster functional recovery compared to controls receiving standard care. The findings highlight…

Ann Surg27 Aug 2025

AI detects surgical site infections accurately from patient wound images.

An innovative AI system accurately detects surgical site infections (SSI) from patient-submitted postoperative wound images, streamlining clinician workload. Among 6,060 patients, the Vision Transformer model achieved a remarkable incision detection accuracy of 94% and an SSI detection accuracy of 73%. It demonstrated effectiveness across diverse…