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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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Endoscopy25 Jun 2025

Digital cholangioscopy is safer than surgery for Mirizzi syndrome

A multicenter study comparing digital single-operator cholangioscopy (DSOC) and surgery for Mirizzi syndrome reveals that despite lower technical success rates, DSOC significantly reduces overall and severe adverse events. Among 290 patients, those undergoing DSOC exhibited fewer complications and lower rates of conversion to open surgery…

Perspectives, Opinions and Curiosities25 Jun 2025

Prehabilitation strategies improve outcomes in digestive cancer surgery

A recent network meta-analysis involving 2042 patients indicates that prehabilitation significantly decreases hospital stay and postoperative complications while enhancing functional recovery. Exercise-based prehabilitation outperformed other strategies for minimizing complications and improving walking distance post-surgery. Multimodal approaches also excelled in improving quality of life and alleviating…

J Surg Res25 Jun 2025

Apixaban reduces VTE rates compared to enoxaparin in surgery

A study investigating postoperative venous thromboembolism (VTE) prophylaxis in colorectal surgery found that patients receiving apixaban had significantly lower rates of VTE (0.16%) compared to those on enoxaparin (1.29%), with a p-value of 0.023. Despite differences in patient demographics, such as age and operative complexity,…

J Robot Surg25 Jun 2025

Robotic-assisted laparoscopic surgery research shows rapid growth

Advancements in robotic-assisted laparoscopic surgery have fostered substantial growth in academic research, particularly after 2019. Analyzing 8,375 publications, the study reveals a surge in productivity and citation impact, with Yonsei University leading contributions. The United States remains dominant in output, while "Surgical Endoscopy" tops volume…

Ann Surg Oncol24 Jun 2025

New staging system enhances prognosis accuracy for gastric cancer

A novel prognostic staging system developed from residual tumor burden significantly outperforms the AJCC’s YpTNM staging in predicting overall survival (OS) and recurrence-free survival (RFS) in patients with locally advanced gastric cancer post-neoadjuvant chemotherapy. The study analyzed data from 537 patients, finding that factors like…

BMC Surg24 Jun 2025

Prehabilitation significantly lowers postoperative mortality and care facility discharges

A department-wide prehabilitation program notably reduced 30-day mortality, discharges to post-acute care facilities, and length of stay for high-risk surgical patients. In a study comparing prehabilitation recipients to matched historical controls, mortality decreased from 2.8% to 0.8%, and discharges to care facilities dropped from 12.9%…

HPB (Oxford)24 Jun 2025

AI Revolutionizes Surgical Video Analysis in Cholecystectomy

AI algorithms were utilized to analyze 481 laparoscopic cholecystectomy videos, revealing that operative time elongated with case complexity. The study found that consultants had a longer duration of anatomy visualization compared to trainees, particularly in complex cases, with the cystic duct often identified before the…

Perspectives, Opinions and Curiosities24 Jun 2025

Lidocaine reduces inflammation and postoperative complications in surgery

Lidocaine, a common local anesthetic, exhibits notable anti-inflammatory and immunomodulatory effects during surgical procedures. It effectively decreases neutrophil and macrophage activation, reduces pro-inflammatory cytokines, and supports endothelial integrity. Benefits of lidocaine include reduced postoperative pain, lower opioid needs, and quicker intestinal recovery. Furthermore, preliminary findings…

Intestine and Lower Gastrointestinal Tract24 Jun 2025

Endoscopic techniques improve outcomes for rectal precancerous lesions.

Innovative endoscopic procedures, including endoscopic submucosal dissection (ESD) and full-thickness resection, significantly enhance treatment for widespread precancerous lesions and early rectal cancers. ESD achieves over 90% R0 resection rates and offers a low recurrence risk of 3%. Notably, lesions up to 20 cm can be…

Surg Endosc23 Jun 2025

Abnormal Demeester Score Predicts Outcomes in Revisional Surgery

Abnormal Demeester scores significantly predict the need for revisional antireflux surgery (ARS) and correlate with improved post-operative outcomes. In a study of 278 patients, those with abnormal scores were more likely to undergo revisional surgery (68.9% vs. 47.3%) and reported higher satisfaction rates (82.9% vs.…