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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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JAMA Surg24 May 2025

Incarcerated individuals face significant barriers to surgical care.

Surgical care for individuals in law enforcement custody is critically compromised, with many facing systemic barriers. Approximately 2 million are incarcerated in the U.S., and age-related surgical needs are rising. Challenges like logistics, privacy, and medical comorbidities result in suboptimal outcomes, with autopsy data indicating…

Am J Surg24 May 2025

EHR workflow reduces time to operating room for surgery patients

A new electronic health records-based workflow has significantly improved the efficiency of surgical consultations at a quaternary referral center. Analysis of 5,724 consultations showed a 27% reduction in time from consultation to operating room, and a remarkable 48% decrease for urgent cases. Length of hospital…

J Hepatobiliary Pancreat Sci24 May 2025

Certification improves surgical outcomes in pancreaticoduodenectomy

An analysis of nearly 79,000 pancreaticoduodenectomy reports from 2014 to 2020 revealed a significant reduction in adjusted odds ratios for surgical mortality—from 0.906 to 0.647. Participation in a nationwide clinical database and surgeon certification system correlated with improved outcomes, including a notable decrease in grade…

Clin Transl Gastroenterol24 May 2025

Lower tumor regression grading enhances survival in gastric cancer.

A meta-analysis of 11 studies revealed that lower tumor regression grades (TRG) significantly correlate with improved disease-free survival (DFS) and overall survival (OS) in patients with locally advanced gastric cancer undergoing neoadjuvant chemotherapy. Specifically, patients with lower TRGs had a DFS hazard ratio of 0.53…

Ulus Travma Acil Cerrahi Derg24 May 2025

Blood glucose regulation significantly improves survival in Fournier’s gangrene

Elevated blood glucose at admission is linked to increased mortality in Fournier's gangrene patients. A study of 36 patients indicated a 16.7% mortality rate, with diabetes common in 61.1% of cases. The optimal glucose cut-off of 186.5 mg/dl provided 83.3% sensitivity and specificity for predicting…

Perspectives, Opinions and Curiosities23 May 2025

ACS NSQIP Risk Calculator Shows Strong Performance in High-Risk Patients

The ACS NSQIP Risk Calculator demonstrated excellent calibration and good discrimination in predicting mortality and morbidity across 21 patient subsets, regardless of risk factors. Observed mortality rates varied significantly, from 0.04% to 60.01%, while morbidity ranged from 3.33% to 59.17%. Both the current machine learning…

Surg Endosc23 May 2025

Robotic pancreaticoduodenectomy lowers complications and hospital stays

A recent study revealed that robotic pancreaticoduodenectomy (RPD) significantly reduces the rate of clinically relevant pancreatic fistulas (10%) compared to open pancreaticoduodenectomy (OPD) (33.3%). Patients undergoing RPD also experienced shorter hospital stays (15 days) versus 22.5 days for OPD. Despite longer operative times for RPD,…

BMJ Open23 May 2025

Nationwide variation in cholecystitis treatment identified.

A nationwide observational study in the Netherlands aims to investigate treatment variations for cholecystitis across 67 hospitals. Despite existing guidelines, adherence to recommended treatments remains low. The study will assess the percentage of patients receiving early cholecystectomy and identify factors influencing guideline adherence. Researchers will…

J Surg Oncol23 May 2025

Early mobilization enhances recovery for abdominal cancer surgery patients

Mobilizing patients with abdominal neoplasms within 24 hours post-surgery significantly improved their mobility compared to those receiving standard physiotherapy. Patients in the intervention group displayed higher mobility scores on the ICU Mobility Scale, both initially and at discharge from the ICU, indicating a positive outcome…

Int J Surg23 May 2025

Intersphincteric complex excision improves survival in rectal cancer.

The intersphincteric complex serves as a metastasis niche in ultralow rectal cancer, with 30.96% of patients showing tumor presence in this area. Complete excision of the complex correlates with significantly improved disease-free survival and local recurrence-free survival rates (HR, 0.382; p=0.008 and HR, 0.251; p=0.012,…